Abstracts - faqs.org

Abstracts

Biological sciences

Search abstracts:
Abstracts » Biological sciences

A common haplotype in the G-protein-coupled receptor gene GPR74 is associated with leanness and increased lipolysis

Article Abstract:

A comprehensive analysis of genetic variance in the G-protein-coupled receptor 74 (GPR74) gene using a large cohort of Swedish subjects was carried out. It was found that the ATAG haplotype was associated with increased adipocyte lipid mobilization in vivo and in vitro suggesting that a common haplotype in the GPR74 gene protects against obesity which is caused by a relief of inhibition of lipid mobilization from adipose tissue.

Author: Hansen, Torben, Arner, Peter, Jorgensen, Torben, Laakso, Markku, Pedersen, Oluf, Blomqvist, Lennart, Kere, Juha, Dahlman, Ingrid, Dicker, Andrea, Hong Jiao, Van Harmelen, Vaness, Hoffstedt, Johan, Borch-Johnsen, Knut
Publisher: University of Chicago Press
Publication Name: American Journal of Human Genetics
Subject: Biological sciences
ISSN: 0002-9297
Year: 2007
G proteins, Leanness, Lipolysis, Report

User Contributions:

Comment about this article or add new information about this topic:

CAPTCHA


ELMOD2 is a candidate gene for familial idiopathic pulmonary fibrosis

Article Abstract:

A genomewide scan in six multiplex families with familal idiopathic pulmonary fibrosis (IPF) is performed originating from southeastern finland. The majority of the Finnish multiplex families are clustered in the region, and the population history suggested that the clustering might be explained by an ancestor shared among the patients.

Author: Hodgson, Ulla, Pulkkinen, Ville, Dixon, Morag, Peyrard-Janvid, Myriam, Rehn, Marko, Lahermo, Paivi, Ollikainen, Vesa, Salmenkivi, Kaisa, Kinnula, Vuokko, Kere, Juha, Tukiainen, Pentti, Laitinen, Tarja
Publisher: University of Chicago Press
Publication Name: American Journal of Human Genetics
Subject: Biological sciences
ISSN: 0002-9297
Year: 2006
Health aspects, Analysis, Diagnosis, In situ hybridization, Immunosuppressive agents, Haplotypes, Pulmonary fibrosis, Clinical report

User Contributions:

Comment about this article or add new information about this topic:

CAPTCHA


Genetic background of congenital chloride diarrhea in high-incidence populations: Finland, Poland, and Saudi Arabia and Kuwait

Article Abstract:

Eight new mutations were found in a study of congenital chloride diarrhea (CLD) among populations in Finland, Poland, Saudi Arabia and Kuwait, bringing the total of known CLD gene mutations to 19. Mutations affect the same locus in all cases studied. Evidence of a major founder effect was seen in the Arab patients.

Author: Kere, Juha, Hoglund, Pia, Auranen, Mari, Socha, Jerzy, Popinska, Kataryna, Nazer, Hisham, Rajaram, Usha, Al Sanie, Abdullah, Al-Ghanim, Mohammed, Holmberg, Christer, De la Chappelle, Albert
Publisher: University of Chicago Press
Publication Name: American Journal of Human Genetics
Subject: Biological sciences
ISSN: 0002-9297
Year: 1998
Saudi Arabia, Poland, Kuwait, Gene mutations, Gene mutation, Diarrhea

User Contributions:

Comment about this article or add new information about this topic:

CAPTCHA


Subjects list: Research, Genetic aspects, Finland
Similar abstracts:
  • Abstracts: A novel adaptor protein orchestrates receptor patterning and cytoskeletal polarity in T-cell contacts. Getting downstream without a Raft
  • Abstracts: Architecture of the Hin synaptic complex during recombination: The recombinase subunits translocate with the DNA strands
  • Abstracts: Polychlorinated biphenyl (PCB)-degrading bacteria associated with trees in a PCB-contaminated site. Degradation of aroclor 1242 dechlorination of products in sediments by Burkholderia xenovarans LB400(ohb) and Rhodococcus sp. strain RHA1(fcb)
  • Abstracts: Diplotype trend regression analysis of the ADH gene cluster and the ALDH2 gene: Multiple significant associations with alcohol dependence
  • Abstracts: Peroxisomal bifunctional protein deficiency revisited: resolution of its true enzymatic and molecular basis. Mutations in the gene encoding peroxisomal sterol carrier protein X (SCPx) cause leukencephalopathy with dystonia and motor neuropathy
This website is not affiliated with document authors or copyright owners. This page is provided for informational purposes only. Unintentional errors are possible.
Some parts © 2023 Advameg, Inc.