An autosomal genomic scan for loci linked to type II diabetes mellitus and body-mass index in Pima Indians

Article Abstract:

Various research methods have been used to identify genetic loci for type II diabetes mellitus occurring in Pima Native Americans. These included variance-components methodology, and multipoint, bivariate linkage and sib-pair analyses, and were adjusted for age and body-mass index. Results indicate potential loci on chromosomes 1q and 7q for diabetes susceptibility.

United States, Health aspects, Diabetes, Native Americans, Native North Americans, Body size, Body weights and measures, Genetic disorders, Diabetes research

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A genomewide association study of skin pigmentation in a south Asian population

Article Abstract:

Single-nucleotide polymorphisms are used in multistage genomewide association study to systematically investigate genetic factors influencing skin-pigmentation variation among South Asian population. Three genes accounting for skin-pigmentation variation are detected.

Science & research, Genetic aspects, Pigmentation disorders, Human genome, Single nucleotide polymorphisms

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