A putative protein complex consisting of Ctf19, Mcm21, and Okp1 represents a missing link in the budding yeast kinetochore

Article Abstract:

A putative protein complex made up of Mcm21, Ctf19, and another protein is a missing link in the budding yeast kinetochore. A one-hybrid screen that makes the in vivo localization of proteins at a functional Saccharomyces cerevisiae centromere possible has been developed. Application found the proteins Mcm21, Ctf19, and the product of an unspecified open reading frame, now named Okp1, all components of the budding yeast centromere. The three likely make up a protein complex linking CBF3, a protein complex associated directly with the CDE III element of the centromere DNA, to other components of the yeast centromere. The CDE III element is both sufficient and essential for localizing the established protein network to the centromere. It is suggested that the interaction of the CDE II element and the CDE III localized protein complex helps a protein-DNA conformation that brings on the active centromere.

Germany, Methods, Genetic aspects, Proteins, Yeast, Yeast (Food product), Chromosomes, Protein research

---

A CBP/p300 homolog specifies multiple differentiation pathways in Caenorhabditis elegans

Article Abstract:

CBP-1, a Caenorhabditis elegans gene, appears to activate differentiation and transcription in C. elegans. It does this by triggering either directly or indirectly the repressive effect of histone deacetylase. The gene is needed during early embryogenesis to indicate differentiation pathways, especially the non-neural pathways of somatic differentiation.

Research, Caenorhabditis elegans, Embryology, Animal embryology, Genetic research

---

Similar abstracts:

• Abstracts: Larval spicules, cilia, and symmetry as remnants of indirect development in the direct developing sea urchin Heliocidaris erythrogramma
• Abstracts: Capping protein levels influence actin assembly and cell motility in dictyostelium. Bacterial motility and signal transduction
• Abstracts: Analysis of the tissue movements of embryonic wound healing: DiI studies in the limb bud stage mouse embryo. Cleavage asynchrony in the Tubifex embryo: involvement of cytoplasmic and nucleus-associated factors
• Abstracts: Distinct adhesive behaviors of neurons and neural precursor cells during regional differentiation in the mammalian forebrain
• Abstracts: Analyses of livestock production, waste storage, and pathogen levels and prevalences in farm manures. Development of a selective medium for isolation of Helicobacter pylori from cattle and beef samples

This website is not affiliated with document authors or copyright owners. This page is provided for informational purposes only. Unintentional errors are possible.