A reassessment of sexual dimorphism in human senescence: Theory, evidence, and causation

Article Abstract:

A theoretical framework for the hypothesis that selection affects senescence in human males and females differently due to different life history characteristics is presented and the necessity of decoupling mortality and senescence when considering sexual dimorphism in senescence is emphasized. If senescence evolves as a result of mutation accumulation, reductions in late-life fitness contributions in women would result in reduced selection against senescence genotypes expressed at later life stages.

Sex, Sexual behavior, Dimorphism (Biology), Sexual behaviour

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The aging brain: The cognitive reserve hypothesis and hominid evolution

Article Abstract:

A study in an attempt to reconcile patterns of brain aging derived from neuroimaging studies with the evolved life history stages of the latter half of the human life span is conducted. A clinical model, 'the cognitive reserve hypothesis', proposes that both increased brain volume and enhanced cognitive ability might contribute to healthy brain aging, reducing the likelihood of developing dementia.

Psychological aspects, Natural history, Cognition, Hominids

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Issues in evolutionary medicine

Article Abstract:

A study illustrates the utility of applying evolutionary thought to medical issues with three examples, selection arenas, aging, and tradeoffs. The method is suggested to get at the mechanism of tradeoffs by examining conflicts among functions over gene expression.

Gene expression, Human biology

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