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A role for the catalytic ribonnucleoprotein RNase P in RNA polymerase III transcription

Article Abstract:

Whole HeLa extracts depleted of ribonuclease P(RNase P), a tRNA-processing ribonnucleoprotein, exhibiting a severe deficiency in RNA polymerase (Pol) III transcription of tRNA and other small, noncoding RNA genes is shown. A role of RNase P in Pol III transcription is demonstrated and it suggests that transcription and early processing of tRNA may be coordinated.

Author: Reiner, Robert, Ben-Asouli, Yitzhak, Krilovetzky, Ilana
Publisher: Cold Spring Harbor Laboratory Press
Publication Name: Genes & Development
Subject: Biological sciences
ISSN: 0890-9369
Year: 2006
RNA polymerases, Transfer RNA, Structure

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RNA-guided RNA modification: Functional organization of the archaeal H/ACA RNP

Article Abstract:

A study has reconstituted functional archaeal H/ACA RNPs from recombinant components, defined the components necessary and sufficient for function, and determined the direct RNA-protein and protein-protein interactions that occur between the components. An insight on the functional organization of this RNPs is provided from the results obtained from the study.

Author: Baker, Daniel L., Youssef, Osama A., Chastkofsky, Michael I.R., Dy, David A., Terns, Rebecca M., Terns, Michael P.
Publisher: Cold Spring Harbor Laboratory Press
Publication Name: Genes & Development
Subject: Biological sciences
ISSN: 0890-9369
Year: 2005
Genetic aspects, Archaeabacteria, Genetic research, Archaea

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Vax genes ventralize the embryonic eye

Article Abstract:

The ventrally expressed homeodomain proteins, Vax 1 and Vax 2 are found to control the neuroepithelial segregation into retina and optic nerve. The absence of these proteins shows that the optic nerve is entirely transformed into fully differentiated retina.

Author: Mui, Stina H., Jin Woo Kim, Lemke, Greq, Bertuzzi, Stefano
Publisher: Cold Spring Harbor Laboratory Press
Publication Name: Genes & Development
Subject: Biological sciences
ISSN: 0890-9369
Year: 2005
Retina, Homeobox genes, Optic nerve

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Subjects list: Research, Noncoding DNA, Proteins
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