A short primer on RNAi: RNA-directed RNA polymerase acts as a key catalyst
Article Abstract:
Research has been conducted on the gene silenced by the RNA interference. The review of the articles on the biochemical and genetic evidence demonstrating that the RNA-directed RNA polymerase chain reaction amplifies interference caused by the trigger dsRNA is presented.
Publication Name: Cell
Subject: Biological sciences
ISSN: 0092-8674
Year: 2001
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Mutations in the RNA component of RNase MRP cause a pleiotropic human disease, cartilage-hair hypoplasia
Article Abstract:
Research has been conducted on the cartilage-hair hypoplasia, an inherited developmental disorder with the predesposition to cancer. The results of the several mutations carried in the untranslated RMRP gene which cosegragate with this disorder are described.
Publication Name: Cell
Subject: Biological sciences
ISSN: 0092-8674
Year: 2001
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Loading Rho to terminate transcription
Article Abstract:
The author reviews the publications on hexameric RNA/DNA helicase Rho required for transcriptional termination mechanisms in bacteria. The topics of interest include the analysis of organization of individual RNA-binding domains.
Publication Name: Cell
Subject: Biological sciences
ISSN: 0092-8674
Year: 2003
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