Aging reduces proliferative capacities of liver by switching pathways of C/EBP(alpha) growth arrest
Article Abstract:
Research has been conducted on liver specific protein C/EBP(alpha) which arrests hepatocyte proliferation via cyclin dependent kinase inhibition. The authors demonstrate that aging leads liver-specific pathways of C/EBP(alpha) growth arrest to E2F transcription repression.
Publisher: Elsevier B.V.
Publication Name: Cell
Subject: Biological sciences
ISSN: 0092-8674
Year: 2003
Aging, Genetic aspects, Liver, Genetic transcription, Transcription (Genetics), Cell proliferation
Publication Name: Cell
Subject: Biological sciences
ISSN: 0092-8674
Year: 2003
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State of the Arg: protein methylation at arginine comes of age
Article Abstract:
The authors review publications on posttranslation protein modification. The topics of interest include the methylation and methyltransferase enzyme function, the effect of the argenine methylation on the protein-protein interactions and the roles of methylation.
Publisher: Elsevier B.V.
Publication Name: Cell
Subject: Biological sciences
ISSN: 0092-8674
Year: 2001
Arginine, Methylation
Publication Name: Cell
Subject: Biological sciences
ISSN: 0092-8674
Year: 2001
User Contributions:
Comment about this article or add new information about this topic:
Subjects list: United States, Analysis, Physiological aspects, Proteins, Cell research, Cytological research
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