Causes, effects, and constraints in the genetics of human longevity
Article Abstract:
The heritability of longevity appears to be low, as it aggregates in families rather than segregating. Genes implicated in longevity probably affect responses to life-threatening factors, rather than directly regulating maximum life span as a distinct trait. Compensatory adaptation is an important factor in aging, involving a long-lasting adaptation in response to a defect in some organic subsystem. Such adaptation leads to a decrease in viability and possibly to irreversible and life-threatening damage associated with aging.
Publication Name: American Journal of Human Genetics
Subject: Biological sciences
ISSN: 0002-9297
Year: 1998
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Arrays of hope
Article Abstract:
The US Food and Drug Administration has launched the MicroArray Quality Control (MAQC) project to probe the microarray technology. Scientists have welcomed the MAQC consortium's Phase I data, but the FDA will have to approve expression-based microarrays so that they can be used for clinical diagnostics.
Publication Name: Cell
Subject: Biological sciences
ISSN: 0092-8674
Year: 2006
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