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Biological sciences

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Cell integrity and morphogenesis in a budding yeast septin mutant

Article Abstract:

A study was performed to show that the non-sporulating diploid strain V327 of Saccharomyces cerevisiae generated a homozygous cdc10 mutation. S. cerevisiae has seven septin-encoding genes in its genome, one of them is CDC10, which code for proteins arranging at the mother-bud neck from late G1 at the developing bud site. Results revealed that cell lysis in the V327 strain occurred only after the expression of an intense morphogenetic phenotype. Cdc10 played a vital role in the morphogenesis of septum development.

Cells (Biology), Morphology (Biology), Cells

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Molecular basis of cell integrity and morphogenesis in Saccharomyces cerevisiae

Article Abstract:

Morphogenesis in Saccharomyces cerevisiae may be understood by combining knowledge of cell wall synthesis and its regulation with knowledge of intracellular signal transduction events. The synthesis and hydrolysis of cell wall polymers is affected by growth of the cell and by environmental conditions. The actin cytoskeleton and the signals that control it have important roles in polarized secretion. These dynamic systems interact to produce morphologic changes.

Analysis, Cell research, Cytological research

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A mutation in the Rho 1-GAP-encoding gene BEM2 of Saccharomyces cerevisiae affects morphogenesis and cell wall functionality

Article Abstract:

A study is conducted to identify the cytological effects of the mutation of the BEM2 gene of Saccharomyces cerevisiae and its role in cell wall functionality. Results show that the formation of a morphogenetic and autolytic phenotype in strain V918 and its segregants is a result of BEM2 mutation. Moreover, the actin cytoskeleton has been depolarized and cell polarity has been lost due to mutation.

Gene mutations, Gene mutation, Bacterial cell walls

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