Centennial: J.B.S. Haldane, 1892-1964
Article Abstract:
John Burdon Sanderson Haldane is popularly credited for developing Haldane's rule for interspecies hybrids and the Briggs-Haldane equations for enzyme kinetics. However, the field of genetics reaped far more than these fruits from this man's incisive and outspoken mind. He contributed much in developing methods for segregation and linkage analysis. He also foresaw the principles behind the maintenance of genetic polymorphism as well as the heterotrophic theory of the origin of life. Outspoken and dogmatic in public, he nevertheless maintained a generous and openminded attitude in science.
Publication Name: Genetics
Subject: Biological sciences
ISSN: 0016-6731
Year: 1992
User Contributions:
Comment about this article or add new information about this topic:
Seventy years ago: mutation becomes experimental
Article Abstract:
Geneticist Herman Joseph Muller became an instant celebrity with his first paper ever to be published entitled 'Artificial Transmutation of the Gene' which focused on gene mutation transpiring within the biological system. One of his earliest findings was that gene mutation caused cancer. He documented several chromosome rearrangements and more mutant genes that were discovered in Drosophila laboratories at the time. All his life, he crusaded against the irresponsible use of high-energy radiation which was based on his belief that there is a direct relationship between dose and mutation.
Publication Name: Genetics
Subject: Biological sciences
ISSN: 0016-6731
Year: 1997
User Contributions:
Comment about this article or add new information about this topic:
Erwin Schrodinger and the hornless cattle problem
Article Abstract:
Erwin Schrodinger was awarded the Nobel Prize for his wave mechanics theory in physics, but geneticists remember him for his book 'What Is Life?'. His book influenced several outstanding scientists and greatly advanced the field of molecular biology. Schrodinger's interest in the gene and its stability attracted physical scientists to shift their interest to molecular genetics. He introduced a genetic problem to a fellow scientist that remains to be unsolved. The problem consisted of equations concerning the breeding of horned and hornless cattles.
Publication Name: Genetics
Subject: Biological sciences
ISSN: 0016-6731
Year: 1992
User Contributions:
Comment about this article or add new information about this topic:
- Abstracts: Dendritic cell subsets and lineages, and their functions in innate and adaptive immunity
- Abstracts: Functional overlap between Sgs1-Top3 and the Mms4-Mus81 endonuclease. Slx1-Slx4 is a second structure-specific endonuclease functionally redundant with Sgs1-Top3
- Abstracts: Repair of oxidative DNA damage in Gram-positive bacteria: the Lactococcus lactis Fpg protein. Use of degenerate primers for polymerase chain reaction cloning and sequencing of the Lactococcus lactis subsp. lactis recA gene
- Abstracts: Induction of folds or sutures on the walls of Cryptosporidium parvum oocysts and their importance as a diagnostic feature
- Abstracts: Binding of the CryIVD toxin of Bacillus thuringiensis subsp. israelensis to larval dipteran midgut proteins. High-level cryIVD and cytA gene expression in Bacillus thuringiensis does not require the 20 kilodalton protein, and the coexprssed gene products are synergistic in their toxicity to mosquitoes