Comparative genetics of resistance to viruses
Article Abstract:
The role that subtle and widespread human gene polymorphisms play in virus-disease resistance is not well understood. The ways in which mouse-virus systems are used to identify candidate virus-resistance genes in humans have been studied. Various benefits can be found in such a study, which provides, among other things, probes to find functional homologues of resistance genes shares by lineages of rodents and primates. Not all of the aspects of virus-restriction are conserved, but functional similarities may be sufficient to be helpful to genetic studies of human resistance to viruses.
Publication Name: American Journal of Human Genetics
Subject: Biological sciences
ISSN: 0002-9297
Year: 1998
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Sex-linked inheritance of endosulphan resistance in Helicoverpa armigera
Article Abstract:
Resistance of Helicoverpa armigera to the insecticide endosulphan is common in Australia. However, resistance frequencies remain around 10%-40% although the insecticide is widely used. Evolution of endosulphan resistance has been studied. Resistance seems to be sex-linked. Nearly complete dosage compensation exists in hemizygous females. Resistance factors in larvae are highest in newborns; they are lower in fifth instar larvae. It seems the genetic basis of resistance would enhance the evolution rate in field populations vs an autosomal locus.
Publication Name: Heredity
Subject: Biological sciences
ISSN: 0018-067X
Year: 1998
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Vicious circles: looking back on resistance plasmids
Article Abstract:
The inheritance of antibiotic resistance genes by bacterial pathogens poses a major problem to the treatment of diseases and infection caused by bacteria. The resistance to antibiotics has been observed during the 1950s, but it was ignored as the phenomenon was not widely prevalent. During the 1980s several species of bacteria such as Pseudomonas aeruginosa, Staphylococcus aureus and Enterococcus faecalis are becoming resistant to the antibiotics which include, chloromphenicol, tetracycline and streptomycin.
Publication Name: Genetics
Subject: Biological sciences
ISSN: 0016-6731
Year: 1995
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