Two enhancers and one silencer located in the introns of regA control somatic cell differentiation in Volvox carteri
Article Abstract:
Research shows that germ-soma differentiation in Volvox carteri is regulated by regA gene whose expression in somatic cells is dependent on introns 3 and 5 and involvement of intron 7 as a silencer of regA in gonidia. Data suggest that the silencer intron 7 functions as a cell-type-specific and promoter-specific enhancer.
Publication Name: Genes & Development
Subject: Biological sciences
ISSN: 0890-9369
Year: 2001
User Contributions:
Comment about this article or add new information about this topic:
Phospholipase C gamma-1 is required downstream of vascular endothelial growth factor during arterial development
Article Abstract:
Research has been conducted on artery formation. The authors have utilized transgenic zebrafish with fluorescently labeled blood vessels to identify and characterize the mutant displaying specific defects in artery formation, and have described the results.
Publication Name: Genes & Development
Subject: Biological sciences
ISSN: 0890-9369
Year: 2003
User Contributions:
Comment about this article or add new information about this topic:
Dwarfism, impaired skin development, skeletal muscle atrophy, delayed bone development, and impeded adipogenesis in mice lacking Akt1 and Akt2
Article Abstract:
Research has been conducted on Akt1 and Akt2 double-knockout mice which exhibit growth deficiency, impaired skin development and severe muscle atrophy. The authors suggest that Akt may be the most critical downstream effector of the IGF-1 receptor during development.
Publication Name: Genes & Development
Subject: Biological sciences
ISSN: 0890-9369
Year: 2003
User Contributions:
Comment about this article or add new information about this topic:
- Abstracts: Synergistic regulation of vertebrate muscle development by Dach2, Eya2, and Six1, homologs of genes required for Drosophila eye formation
- Abstracts: Mismatch repair-dependent processing of methylation damage gives rise to persistent single-stranded gaps in newly replicated DNA
- Abstracts: A novel, putative MEK kinase controls developmental timing and spatial patterning in Dictyostelium and is regulated by ubiquitin-mediated protein degradation