Quantitative approach in the study of adhesion of lactic acid bacteria to intestinal cells and their competition with enterobacteria

Article Abstract:

A mathematical model is presented to describe and analyze bacterial adhesion to Caco-2 cells and intestinal mucus and the affinity of the attachment. Adhesion kinetics between populations of bacteria indicate presence of single and multiple adhesion sites.

Author: Lee, Y.K., Lim, C.Y., Teng, W.L., Ouwehand, A.C., Tuomola, E.M., Salminen, S.
United States, Singapore, Statistical Data Included, Analysis, Bacteria, Intestines, Intestinal microbiology, Cell adhesion molecules, Bacterial adhesion

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Effects of polyunsaturated fatty acids in growth medium on lipid composition and on physicochemical surface properties of lactobacilli

Article Abstract:

Results show that lactobacilli in the presence of free polyunsaturated fatty acids in the growth medium induce changes in the fatty acid profile, which in turn regulates the degree of fatty acid unsaturation, cyclization, and ratio of conjugated linoleic acid and polyunsaturated fatty acids, which influence cell surface properties of lactobacilli.

Author: Salminen, S., Isolauri, E., Kankaanpaa, P., Yang, B., Kallio, H.
Drugs, In-Vitro Diagnostic Substance Manufacturing, All Other Miscellaneous Chemical Product and Preparation Manufacturing, Chemical preparations, not elsewhere classified, Culture Media & Products, Culture Media, Unsaturated Fatty Acids, Influence, Microbiological synthesis, Culture media (Biology), Composition, Statistics, Statistics (Data), Surface chemistry

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Intestinal mucus alters the ability of probiotic bacteria to bind aflatoxin B1 in vitro

Article Abstract:

Studies done to determine whether AFB1 and intestinal mucus influence each otherEs binding by surface structures of two probiotic preparations are reported. The results reveal that probiotics adhering to the intestinal wall are less likely to bind and consequently accumulate AFB1 in the host and on the other hand probiotics with AFB1 bound to their surfaces are less likely to adhere to the intestinal wall and prolong expose to dietary AFB1. It is concluded that specific probiotics may be potent and safe means to reduce absorption and increase excretion of dietary AFB1 from the body.

Author: Mykkanen, H., Ouwehand, A.C., Salminen, S., Gratz, S., Juvonen, R., El-Nezami, H.
Observations, DNA-ligand interactions, DNA binding, Probiotics, Aflatoxins

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Subjects list: Finland, Physiological aspects, Lactobacillus, Research
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