Endophytic taxol-producing fungi from bald cypress, Taxodium distichum

Article Abstract:

The endophyte Pestalotiopsis microspora, which is present as a range of strains in bald cypress, Taxodium distichum, produces taxol. These taxol-producing fungi reside in the bark, phloem and xylem. They produce taxol as determined by the reactivity of partially purified culture extracts with specific monoclonal antibodies against taxol. One of its strains was found through chromatography and spectroscopy to have taxol identical to authentic taxol. The occurrence of these organisms in T. distichum suggests that taxol-producing endophytes may also be living in other plant species in damp environments.

Endophytes, Cypress

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A novel glycosylated Cu/Zn-containing superoxide dismutase: production and potential therapeutic effect

Article Abstract:

A novel glycosylated Cu/Zn-containing superoxide dismutase (SOD) has been studied with attention to production and potential therapeutic effect. Humicola lutea 103, a fungal strain, produces a naturally glycosylated Cu/Zn SOD. H. lutea Cu/Zn SOD was used in an in vivo model for the demonstration of its protectiv effect against myeloid Graffi tumor in hamsters. Results suggest appropriate use of the novel fungal SOD, alone or in combination with selective inhibitors, might be suitable for use in treatment of myeloid Graffi tumor and influenza virus infections.

Germany, Bulgaria, Statistical Data Included, Usage, Reports, Influenza research, Viral research, Proteins, Virus research, Tumors, Zinc, Copper, Catalysis, Superoxide dismutase

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Disordered ultrastructure in lignin-peroxidase-secreting hyphae of the white-rot fungus Phanerochaete chrysosporium

Article Abstract:

Exposure of the white-rot fungus Phanerochaete chrysosporium to pure oxygen causes a loss of cellular ultrastructure. This fungus is usually exposed to pure oxygen to induce lignin peroxidase synthesis.

Oxidation, Physiological, Physiological oxidation

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