An HMG1-like protein facilitates Wnt signaling in 'Caenorhabditis elegans'

Article Abstract:

A protein similar to HMG1 encourages Wnt signaling in gene transcription regulation. Using Caenorhabditis elegans as subjects, SON-1 exhibited HMG1-like traits such as cell fate transformation in several developmental processes, including somatic gonad development, male tail patterning and vulva development. SON-1 acts downstream within the Wnt signaling pathway, also similar to HMG1 activity.

United States, Proteins, DNA binding proteins, Cell physiology

---

A functional study of miR-124 in the developing neural tube

Article Abstract:

The chick spinal cord as an in vivo system was employed to investigate the role of miR-124 during neural development. It was found that neither inhibition nor ectopic expression of miR-24 markedly altered general neuronal differentiation, suggesting that miR-124 does not act as determinant of neuronal differentiation.

Science & research, Genetic aspects, Developmental genetics, Developmental neurology

---

Similar abstracts:

• Abstracts: Evolutionary conservation of cell migration genes: From nematode neurons to vertebrate neural crest. MyoD, modularity, and myogenesis: Conservation of regulators and redundancy in C. elegans
• Abstracts: Human molybdopterin syntase gene: identification of a bicistronic transcript with overlapping reading frames. Long-term rescue of a lethal inherited disease by adeno-associated virus-mediated gene transfer in a mouse model of molybdenum-cofactor deficiency
• Abstracts: PCR amplification and species determination of microsporidia in formalin-fixed feces after immunomagnetic separation

This website is not affiliated with document authors or copyright owners. This page is provided for informational purposes only. Unintentional errors are possible.