Mechanistic flexibility as a conserved theme across 3 billion years of nonhomologous DNA end-joining
Article Abstract:
The article discusses the distinctive repair pathways and the mechanisms involved in the mending of the nonhomologous DNA end-joining (NHEJ). The mechanistic flexibility of the bacteria is found to play an extremely significant role in NHEJ, which can be further employed in the infectious disease researches.
Publisher: Cold Spring Harbor Laboratory Press
Publication Name: Genes & Development
Subject: Biological sciences
ISSN: 0890-9369
Year: 2008
Genetic aspects, Eukaryotes, DNA polymerases, New Guineans
Publication Name: Genes & Development
Subject: Biological sciences
ISSN: 0890-9369
Year: 2008
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Cellular machineries for chromosomal DNA repair
Article Abstract:
A human cell must constantly repair over 10,000 DNA lesions per day to counteract endogenous sources of DNA damage. Recent studies on the cellular machinery that facilitates DNA repair within the context of chromatin are reviewed.
Publisher: Cold Spring Harbor Laboratory Press
Publication Name: Genes & Development
Subject: Biological sciences
ISSN: 0890-9369
Year: 2004
Chromosomes, Genetic research
Publication Name: Genes & Development
Subject: Biological sciences
ISSN: 0890-9369
Year: 2004
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Subjects list: Research, DNA repair
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