Characterization of apparently balanced chromosomal rearrangements from the Developmental Genome Anatomy Project

Article Abstract:

The Developmental Genome Anatomy Project (DGAP) aims at identifying and characterizing the different genes related to the apparently balanced chromosomal rearrangements in human bodies. These rearrangements are found to be extremely beneficial in studying the gene discovery and annotation.

Author: Harris, David J., Bruns, Gail A.P., Gusella, James F., Morton, Cynthia C., Leach, Natalia T., Korf, Bruce R., Quade, Bradley J., Maas, Richard L., Kulkarni, Shashikant, Hyung-Goo Kim, Yanli Fan, Ligon, Azra H., Kishikawa, Shotaro, Higgins, Anne W., Donovan, Diana J., Lally, Eric, Alkuraya, Fowzan S., Bosco, Amy F., Brown, Kerry K., Eisenman, Robert, Farra, Chantal G., Ferguson, Heather L., Herrick, Steven R., Kelly, Chantal, Lemyre, Emma, Lewis, Janine, Moore, Steven D.P., Peters, Roxanna E., Quintero-Rivera, Fabiola, Saadi, Irfan, Shendure, Jay, Williamson, Robin E.
Publisher: University of Chicago Press
Publication Name: American Journal of Human Genetics
Subject: Biological sciences
ISSN: 0002-9297
Year: 2008
Analysis, Polymerase chain reaction, Genomes, Chromosome replication, Human anatomy

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DNA methylation signatures within the human brain

Article Abstract:

Brain samples from individuals are analyzed and quantitative to determine the DNA methylation levels representing genes with diverse functions. The DNA methylation signatures distinguish brain regions and help account for region-specific functional programs.

Author: Feinberg, Andrew P., Pevsner, Jonathan, Callinan, Pauline A., Ladd-Acosta, Christine, Sabunciyan, Sarven, Yolken, Robert H., Webster, Maree J., Dinkins, Tiffany, Fan, Jian-Bing, Potash, James B.
Publisher: University of Chicago Press
Publication Name: American Journal of Human Genetics
Subject: Biological sciences
ISSN: 0002-9297
Year: 2007
Biological Product (except Diagnostic) Manufacturing, Drugs, Deoxyribonucleic Acid, DNA, Brain research, Gene expression, Methylation, Chemical properties, Human genome

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Subjects list: Research
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