Influences of biofilm structure and antibiotic resistance mechanisms on indirect pathogenicity in a model polymicrobial biofilm

Article Abstract:

An investigation was conducted on the contributions of antibiotic resistance mechanisms and biofilm structure to indirect pathogenicity (IP) within polymicrobial biofilms using a model two-member consortium. Escherichia coli ATC 33456 was converted with vectors conferring either ampicillin or spectinomycin resistance, creating two distinct populations with different resistance mechanisms.

United States, Structure

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Escherichia coli biofilms formed under low-shear modeled microgravity in a ground-based system

Article Abstract:

A low-shear modeled microgravity is described in a ground-based system (LSMMG), involving the use of glass microcarriers in high-aspect-ratio vessels (HARVs). The biofilms of a mutant of Escherichia coli are impaired in developing LSMMG-conferred resistance to the general stressors but not to the antibiotics, which have indicated two separate pathways of LSMMG-conferred resistance.

Escherichia coli, Report

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Multiparameter assessments to determine the effects of sugars and antimicrobials on a polymicrobial oral biofilm

Article Abstract:

The development of procedures for simultaneous assessment of the diverse nonmicrobial biofilm components were investigated for multiparameter analysis. It demonstrated contrasting effects of the tested antibiotics on biofilm components for multiparameter assessments.

New Jersey, Analytical Laboratory Instrument Manufacturing, Analytical instruments, Scanning Microscopy, Analysis, Observations, Growth, Fluorescence, Company growth

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