Inositol monophosphatase regulates localization of synaptic components and behavior in the mature nervous systems of C. elegans

Article Abstract:

A study is conducted to show that mutations in thermotaxis (ttx-7) cause defects in thermotaxis behavior in the nematode Caenorhabditis elegans and localization of synaptic proteins in RIA neurons in vivo. The results have suggested that myo-inositol monophosphatase (IMPase) is required in central interneurons of the mature nervous system for correct localization of synaptic components and thus for normal behavior.

Gene mutations, Gene mutation, Genetic research

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Control of C. elegans hermaphrodite gonad size and shape by vab-3/Pax-6-mediated regulation of integrin receptors

Article Abstract:

Control of Caenorhabditis elegans hermaphrodite gonad size and shape by vab-3/Pax-6-mediated regulation of integrin receptors is described. It is shown that the downregulation of ina-1, an [alpha] integrin gene is necessary for distal tip cell (DTC) migration cessation and up-regulation of pat-2 is required for directionality.

Genetic regulation, Integrins

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Control of sex-specific apoptosis in C. elegans by the BarH homeodomain protein CEH-30 and the transcriptional repressor UNC-37/Groucho

Article Abstract:

The various effects of the BarH homeodomain protein CEH-30 and the transcriptional repressor UNC-37/Groucho on the sex-specific apoptosis in Caenorhabditis elegans are discussed.

Homeostasis, Dimorphism (Biology), Apoptosis

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