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Biological sciences

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Isolation and characterization of a bacteriocin (Butyrivibriocin AR10) from the ruminal anaerobe Butyrivibrio fibrisolvens AR10: evidence in support of the widespread occurrence of bacteriocin-like activity among ruminal isolates of B.fibrisolvens

Article Abstract:

The isolation and purification of bacteriocin, Butyrivibriocin AR10 from the ruminal anaerobe, Butyrivibrio fibrisolvens AR10, indicates that bacteriocin-like activity is a common feature in this genus. The inhibitory activity of B.fibyrisolvens AR10 is due to the presence of a single peptide. The bacteriocin has a high content of nonpolar amino acids residues. The N terminus of the peptide is blocked and a cyanogen bromide cleavage fragment of the native peptide yields a sequence of 20 amino acids.

Antibacterial agents, Structure-activity relationships (Pharmacology), Ruminants

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Evidence for production of a new lantibiotic (butyrivibriocin OR79A) by the ruminal anaerobe Butyrivibrio fibrisolvens OR79: characterization of the structural gene encoding butyrivibriocin OR79A

Article Abstract:

The ruminal anaerobe Butyrivibrio fibrisolvens OR79 has been demonstrated to produce lantibiotics which are closely related to lantibiotics earlier isolated from the lactic acid bacteria, despite the phylogenetic distance. With butyrivibriocin OR79 representing the second bacteriocin to be isolated from a Butyrivibrio strain of ruminal origin and characterized, bacteriocins from both major groups of peptide antibiotics have now been isolated from B fibrisolvens and characterized.

Physiological aspects, Bacteria

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Identification of bacteriocin-like inhibitors from rumen Streptococcus spp. and isolation and characterization of bovicin 255

Article Abstract:

A bacteriocin from Streptococcus spp. similar to class II bacteriocins of gram-positive bacteria has been isolated from bovine rumen. The properties of bovicin 255 are described.

Streptococcus, Bacterial toxins

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