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Biological sciences

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Isolation and characterization of a variety of microcystins from seven strains of the cyanobacterial genus Anabaena

Article Abstract:

Microcystins were extracted from seven freshwater Anabaena strains, purified and analyzed. Each strain produced three to seven different compounds. Eight out of the 17 compounds isolated were known microcystins. The remainining nine are new microcystins. Six of the eight were isolated for the first time from Anabaena strains. The number of cells used for extraction appeared to influence the number of toxins per strain. The time of isolation also seemed to affect the types of toxin produced and the morphology of the bacteria. Toxin production was similar regardless of location of the strain's origin.

Health aspects, Bacterial toxins, Freshwater algae

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Evidence for paralytic shellfish poisons in the freshwater cyanobacterium Lyngbya wollei (Farlow ex Gomont) comb. nov

Article Abstract:

Isolates of Lyngbya wollei collected from the Gunterville Reservoir secrete neurotoxins that are similar to paralytic shellfish toxins in lethality when tested using the mouse bioassay. The bioassay was very effective in screening the neurotoxins from the hepatoxins by observing signs of poisoning and survival times. Lyngbya wollei is a cyanobacterium found in most lakes and reservoirs in southeastern US. It has been observed for the last 100 years but has been more prevalent since the 1970s.

Analysis, Neurotoxic agents

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Isolation and identification of eight microcystins from thirteen Oscillatoria agardhii strains and structure of a new microcystin

Article Abstract:

Microcystins are cyclic heptapeptide hepatotoxins of algal blooms. The variation in microcystins isolated from 13 Finnish Oscillatoria agardhii strains were investigated. The 13 strains yielded eight different microcystins, of which five were previously known and three were new. The structure of one of the new microcystins was determined to be an Mser variant of MCYST-RR, and is possibly a biosynthetic precursor of the principal toxin.

Water bloom, Algal blooms, Microbial toxins

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