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Isolation, partial characterization, and mode of action of acidocin J1132, a two-component bacteriocin produced by Lactobacillus acidophilus JCM 1132

Article Abstract:

A novel bacteriocin produced by Lactobacillus acidophilus called acidocin J1132 has been isolated and partially characterized. Acidocin J1132 features a narroe antimicrobial spectrum and shares characteristics with a family og class II LAB bacteriocins. The antimicrobial activity of the unique bacteriocin is caused by the activities of two components termed alpha and beta. J1132 elevates the permeability of the cytoplasmic membrane of target cells by triggering dissipation of the proton motive force and forming voltage-independent pores.

Author: Kanatani, Kazuo, Oshimura, Masao, Tahara, Takatsugu, Umezawa, Chisae
Publisher: American Society for Microbiology
Publication Name: Applied and Environmental Microbiology
Subject: Biological sciences
ISSN: 0099-2240
Year: 1996
Bacteria, Microorganisms, Lactobacillus acidophilus

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Jenseniin G, a heat-stable bacteriocin produced by Propionibacterium jensenii P126

Article Abstract:

A heat-stable inhibitor, jenseniin G, produced by Propionibacterium jensenii P126 was characterized. The bacteriocin was found to inhibit two related strains P. jensenii P54 and P. acidipropionici, and various lactic acid bacteria. Further tests showed that the bacteriocin was inactivated by pronase E, type 14 protease and proteinase K but insensitive to catalase. It was also stable at temperatures of 4 degrees centigrade for days and 100 degress centigrade for 15 minutes.

Author: Grinstead, D.A., Barefoot, S.F.
Publisher: American Society for Microbiology
Publication Name: Applied and Environmental Microbiology
Subject: Biological sciences
ISSN: 0099-2240
Year: 1992
Antibacterial agents

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Bacteriocin T8, a novel class IIa sec-dependent bacteriocin produced by Enterococcus faecium T8, isolated from vaginal secretions of children infected with human immunodeficiency virus

Article Abstract:

Enterococcus faecium T8, isolated from vaginal secretions of children with human immunodeficiency virus, creates a class IIa sec-dependent bacteriocin that is structurally different from three other class IIa sec-dependent bacteriocins. It was found that bacteriocin T8 is active against E. faecalis isolated from patients diagnosed with vaginosis, against Lactobacillus sakei, and against a Propionibacterium sp.

Author: De Kwaadsteniet, M., Fraser, T., Van Reenen, C.A., Dicks, L.M.T.
Publisher: American Society for Microbiology
Publication Name: Applied and Environmental Microbiology
Subject: Biological sciences
ISSN: 0099-2240
Year: 2006
Science & research, Health aspects, Risk factors, HIV infection in children, Pediatric HIV infections, Bacteriocins, Nucleotide sequencing

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Subjects list: Research, Analysis
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