Abstracts - faqs.org

Abstracts

Biological sciences

Search abstracts:
Abstracts » Biological sciences

Lamin A/C and emerin are critical for skeletal muscle satellite cell differentiation

Article Abstract:

A study to show that cultured muscle cells from lamin A/C knockout mice exhibit impaired differentiation kinetics and reduced differentiation potential is presented. These studies indicate roles for A-type lamins and emerin in myogenic differentiation and also suggest that these effects are at least in part due to decreased endogenous levels of other critical myoblast proteins.

Author: Kennedy, Brian K., Frock, Richard L., Kudlow, Brian A., Evans, Angela M., Jameson, Samantha A., Hauschka, Stephen D.
Publisher: Cold Spring Harbor Laboratory Press
Publication Name: Genes & Development
Subject: Biological sciences
ISSN: 0890-9369
Year: 2006
Genetic aspects, Muscles, Myogenesis, Skeletal muscle

User Contributions:

Comment about this article or add new information about this topic:

CAPTCHA


The polycomb Ezh2 methyltransferase regulates muscle gene expression and skeletal muscle differentiation

Article Abstract:

Ezh2 expression was developmentally regulated in the myotome compartment of mouse somites and its down-regulation coincided with activation of muscle gene expression and differentiation of satellite-cell-derived myoblasts. Both Ezh2 and YY1 were detected, with the deacetylase HDAC1 at genomic regions of silent muscle-specific genes.

Author: Caretti, Giuseppina, Di Padova, Monica, Micales, Bruce, Lyons, Gary E., Sartorelli, Vittorio
Publisher: Cold Spring Harbor Laboratory Press
Publication Name: Genes & Development
Subject: Biological sciences
ISSN: 0890-9369
Year: 2004
Gene expression, Somite, Somites (Embryology)

User Contributions:

Comment about this article or add new information about this topic:

CAPTCHA



Subjects list: Research, Cell differentiation
Similar abstracts:
  • Abstracts: Integration of Smad and forkhead pathways in the control of neuroepithelial and glioblastoma cell proliferation
  • Abstracts: SUMO and ubiquitin in the nucleus: different functions, similar mechanism?. Segmentation in vertebrates: clock and gradient finally joined
  • Abstracts: Regulation by let-7 and lin-4 miRNAs results in target mRNA degradation. The nucleosome: from genomic organization to genomic regulation
  • Abstracts: The sins of the fathers and mothers: genomic imprinting in mammalian development. The genetic basis for specific anosmia to isovaleric acid in the mouse
  • Abstracts: In vivo ablation of surface immunoglobulin on mature B cells by inducible gene targeting results in rapid cell death
This website is not affiliated with document authors or copyright owners. This page is provided for informational purposes only. Unintentional errors are possible.
Some parts © 2025 Advameg, Inc.