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Mechanisms of Drosophila retinal morphogenesis: the virtues of being progressive

Article Abstract:

The differentiation in the fly Drosophila's eye follows a repetitive cycle of induction in such an advanced mechanism resulting in unusual precision. The adult fly eye has 800 individual eyes (ommatidia) arranged in a two-dimensional lattice, the precision of which is essential for proper vision. The arrangement of the eye starts from the posterior margin of the epithelium and proceeds towards the eye disk with each subsequent eye being arranged in an organized manner such that a preceding row is a template for the next.

Author: Moses, Kevin, Heberlein, Ulrike
Publisher: Elsevier B.V.
Publication Name: Cell
Subject: Biological sciences
ISSN: 0092-8674
Year: 1995
Eye, Anatomy

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Cloning and functional analysis of TipE, a novel membrane protein that enhances Drosophila para sodium channel function

Article Abstract:

The tipE gene in Drosophila controls the activity of the para sodium channel and the development of the nervous system. The tipE gene is present on the 3rd chromosome and a mutated gene which produces a truncated protein is unable to prevent the paralytic phenotype but rescues adult flies from heat-induced lethality. Thus the expression of tipE during the middle to late pupal stage is necessary to prevent paralysis. Overexpression of tipE in tipE mutant adults does not prevent paralysis.

Author: Feng, Guoping, Deak, Peter, Hall, Linda M., Chopra, Maninder
Publisher: Elsevier B.V.
Publication Name: Cell
Subject: Biological sciences
ISSN: 0092-8674
Year: 1995
Developmental neurology, Sodium channels

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Cell-cell signaling, microtubules, and the loss of symmetry in the Drosophila oocyte

Article Abstract:

The interactions between the germ cells and the somatic cells give rise to the dorsal-ventral and anterior-posterior axes of the Drosophila oocyte. The subcellular organization of the oocyte is crucial for the development of the embryo. The coordination of the embryonic axis in frogs and flies occurs through polarization of the oocyte. The orientation of the microtubule network is responsible for the transport and sorting of RNA and proteins inside the oocyte.

Author: Lehmann, Ruth
Publisher: Elsevier B.V.
Publication Name: Cell
Subject: Biological sciences
ISSN: 0092-8674
Year: 1995
Analysis, Oocytes, Oocyte donation

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Subjects list: Research, Observations, Cell differentiation, Drosophila
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