Molecular characterization of Mycobacterium isolated from seals

Article Abstract:

A study to evaluate epidemiological relationship and genetic characteristics of the mycobacteria that cause tuberculosis (TB) in seals in South America is discussed. A new technique called spoligotyping, based on the in vitro amplification of the DNA sequence of the highly polymorphic direct repeat locus in the chromosome of M. tuberculosis complex members, was designed.

Spain, Uruguay, Health aspects, Research, Natural history, Tuberculosis, Mycobacterium tuberculosis, South America, Cytochemistry, Seals (Animals)

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The gene encoding P27 lipoprotein and a putative antibiotic-resistance gene form an operon in Mycobacterium tuberculosis and Mycobacterium bovis

Article Abstract:

Results show that an open reading frame sequence and P27 gene sequence are separated only by six bases resulting in a polycistronic (operon) nature of both genes. Data indicate that the genes code for membrane proteins involved in the antibiotic resistance and tranport in Mycobacteria.

Observations, Drug resistance in microorganisms, Microbial drug resistance, Membrane proteins, Mycobacteria, Mycobacterium, Lipoproteins

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Expansion of growth substrate range in Pseudomonas putida F1 by mutations in both cymR and todS, which recruit a ring-fission hydrolase CmtE and induce the tod catabolic operon, respectively

Article Abstract:

Results demonstrate that Pseudomonas putida F1 strains capable of growing on a variety of substrates exhibit mutations to recruit CmtE, ameta-cleavage product hydrolase of cmt operon, for inducing the tod catabolic operon on new growth substrates.

South Korea, Bacterial growth, Pseudomonas putida, Microbial mutation

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