Myogenesis: a view from Drosophila

Article Abstract:

A model of muscle development in Drosophila is presented. Based on the model, myogenesis takes place with the segregation of specific myoblast subtypes. There are founders and fusion competent cells in presumptive muscle tissues. Without founder cells fusion cannot take place between fusion competent myoblasts. This model provides some explanation for myogenesis in flies but the understanding of the process is still limited.

Insects

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Mergers and acquisitions: unequal partnerships in Drosophila myoblast fusion

Article Abstract:

This review discusses the role of cell type-specific cell surface molecules in the process of myoblast fusion using Drosophila as a model. Data indicate that in Drosophila, founder cells recruit the fusion-competent cells which eventually fuse with the former and initiate muscle differentiation.

Germany, Cell interaction, Cell interactions

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Drosophila dumbfounded: a myoblast attractant essential for fusion

Article Abstract:

Results show that the gene dumbfounded encodes a protein which aids in the aggregation and fusion of myoblasts in Drosophila.

United Kingdom, Embryology, Animal embryology

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