Myogenin's functions do not overlap with those of MyoD or Myf-5 during mouse embryogenesis
Article Abstract:
Gene knockout experiments show that genes that code for the myogenic basic helix-loop-helix proteins have their own unique pattern of expression. Of the four genes, MyoD and Myf-5 have overlapping roles in the generation of myoblasts. Mice double homozygous for null mutations in MyoD and myogenin or Myf-5 and myogenin exhibited embryonic and perinatal phenotypes similar to those observed in mice mutant for each gene alone. These results suggest that the function of myogenin does not overlap with those of MyoD or Myf-5 during embryogenesis.
Publication Name: Developmental Biology
Subject: Biological sciences
ISSN: 0012-1606
Year: 1995
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Pax6 is required for delta-catenin/neurojugin expression during retinal, cerebellar and cortical development in mice
Article Abstract:
The regulation of central nervous system through neurojugin expression by paired box gene 6 is analyzed.
Publication Name: Developmental Biology
Subject: Biological sciences
ISSN: 0012-1606
Year: 2006
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