A murine model of Holt-Oram syndrome defines roles of the T-box transcription factor Tbx5 in cardiogenesis and disease
Article Abstract:
Research has been conducted on the T-box proteins. The role of these proteins in cardiac development and the consequences of the TBX5 mutations have been investigated via the engineered mice containing a deletion in Tbx5 alleles and the results are discussed.
Publisher: Elsevier B.V.
Publication Name: Cell
Subject: Biological sciences
ISSN: 0092-8674
Year: 2001
Canada, Germany, Physiological aspects, Gene mutations, Gene mutation, Proteins, Genetic transcription, Transcription (Genetics), Cardia
Publication Name: Cell
Subject: Biological sciences
ISSN: 0092-8674
Year: 2001
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After the genome: DNA and human disease
Article Abstract:
The purpose of this article is to discuss the human genetics research. The author overviews the publications on the major genetic disorders- Duchenne muscular dystrophy, chronic granulomatous disease and retinoblastoma.
Publisher: Elsevier B.V.
Publication Name: Cell
Subject: Biological sciences
ISSN: 0092-8674
Year: 2001
Causes of, DNA, Genomes, Genetic disorders, Retinoblastoma, Duchenne muscular dystrophy, Chronic granulomatous disease
Publication Name: Cell
Subject: Biological sciences
ISSN: 0092-8674
Year: 2001
User Contributions:
Comment about this article or add new information about this topic:
Subjects list: Statistical Data Included, United States, Analysis, Genetic aspects, Cell research, Cytological research
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