P-bodies react to stress and nonsense
Article Abstract:
Translational repression and messenger ribonucleic acid (mRNA) turnover might occur in P-bodies, which are specialized cytoplasmic compartments. Results of one study indicate that normal mRNA can be released from P-bodies and translated into protein in response to stress, while another study reports that aberrant mRNAs are targeted to P-bodies to undergo rapid decay.
Publication Name: Cell
Subject: Biological sciences
ISSN: 0092-8674
Year: 2006
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The double lives of shuttling mRNA binding proteins
Article Abstract:
This review examines the process of mRNA transport from the nucleus to cytoplasm and its interaction with regulatory proteins before culminating in the generation of a protein in the cytoplasm. Recent data point out that RNA binding proteins called heterogeneous nuclear ribonucleoproteins play a role in this mRNA metabolism.
Publication Name: Cell
Subject: Biological sciences
ISSN: 0092-8674
Year: 2000
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Rhox: A new homeobox gene cluster
Article Abstract:
The discovery of a cluster of 12 related homeobox genes on the X chromosome expressed in male and female reproductive tissues in adult mice are reported. These reproductive homeobox on the X chromosome genes are expressed in cell type-specific manner.
Publication Name: Cell
Subject: Biological sciences
ISSN: 0092-8674
Year: 2005
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- Abstracts: When duplicated genes don't stick to the rules. The rise and falls of introns. Adaptive evolution or genetic drift? Does genome complexity produce organismal complexity?
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