Abstracts » Biological sciences

Peptide ligands that bind selectively to spores of Bacillus subtilis and closely related species

Article Abstract:

A model detection system involving a peptide ligands that bind tightly to spores of Bacillus subtilis and a standard small-molecule ligand capable of binding this spore is constructed. The results suggested that short peptides could be used as species-specific ligands and suggest that other short peptides can be isolated as specific ligands for different spores species and perhaps for any cell type.

Environmental aspects, Bacillus subtilis, Ligand binding (Biochemistry)

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Thermal inactivation of Bacillus anthracis spores in cow's milk

Article Abstract:

Decimal reduction time (time to inactivate 90% of the population) (D) values of Bacillus anthracis spores in milk ranged from 3.4 to 16.7 h at 72 degree Celsius and from 1.6 to 3.3 s at 112 degree Celsius. The calculated increase of temperature needed to reduce the D value by 90% varied from 8.7 to 11.0 degree Celsius, and the Arrhenius activation energies ranged from 227.4 to 291.3 kJ/mol.

Methods, Milk, Milk pasteurization

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Species-specific peptide ligands for the detection of Bacillus anthracis spores

Article Abstract:

Research describes the synthesis of peptide ligands specific to Bacillus anthracis spores and to spores from a phylogeneticlly similar variant of B. anthacis. The petide sequences are ATYPLPIR abd SLLPGLP, respectively. Data indicate that the peptides are highly specific without any false-positive binding.

United States, Evaluation, Design and construction, Binding proteins

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