Postmeiotic transcription of X and Y chromosomal genes during spermatogenesis in the mouse

Article Abstract:

The Xist gene does not seem to be involved in X chromosome inactivation during spermatogenesis in the mouse. Both X and Y chromosomes are inactive only during the meiotic prophase of spermatogenesis. Postmeiotic expression of the X chromosomal gene Ube1x has been demonstrated, as well as a temporary postmeiotic expression of MHR6A, another X chromosomal gene, and differential postmeiotic expression of the Y chromosomal genes Ube1y and Sry. The X chromosome's postmeiotic activity is a new finding, one that can perhaps lead to better understanding of X chromosome inactivation during spermatogenesis and paternal genome imprinting.

Analysis, Spermatogenesis, Chromosomal proteins

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Developmental and photoregulation of al-1 and al-2, structural genes for two enzymes essential for carotenoid biosynthesis in Neurospora

Article Abstract:

A study was conducted to examine the effects of light and development during the development of asexual spores in Neurospora crassa. During conidiation, low lighting levels resulted to accumulation of al-1 and al-2 mRNAs, with albino message accumulation increasing as the process proceeds. Such result was not observed in two Neurospora mutants, wc-1 and wc-2, which were blocked at certain stages during conidiation. This suggests that light induces increases in albino gene transcript levels.

Genetic aspects, Gene expression, Carotenoid metabolism, Neurospora

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Conservation of mammalian secondary sperm receptor genes enables the promoter of the human gene to function in mouse oocytes

Article Abstract:

A study conducted to describe the human ZP2 gene and its coding sequences reveal a 70% similarity with the mouse Zp-2 gene. This similarity, plus the fact that both genes are well conserved, enabled the human ZP2 to remain active after transcription to mouse oocytes. The reporter gene activity that resulted from the transcription matches that of the homologous mouse promoter gene.

Genetic engineering, Promoters (Genetics)

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