Seeking new antibiotics in nature's backyard

Article Abstract:

The pipeline of new antibiotics approved by the US Food and Drug Administration (FDA) is running dry despite the threat of a new form of multidrug resistant strain of Mycobacterium that leaves patients virtually untreatable with current anti-TB drugs. Researchers screened 480 strains of soil bacteria from different environments against 21 antibiotics and found them to be resistant on average to 7 antibiotics, which spells doom, but opens opportunity to look for resistance mechanisms in nature as an early warning system before they are found in hospital bacteria.

Science & research, Care and treatment, Research, Antibiotics, Drug resistance in microorganisms, Microbial drug resistance, Bacterial infections, Report

---

Malaria: New vaccines for old?

Article Abstract:

The difficulties that scientists face when developing a vaccine against malaria is summarized. Genome and post-genome research is providing potential candidate proteins for a malaria vaccine and the current challenge is to provide further validation of these proteins such that they may enter the pipeline for vaccine development in a rational fashion.

Drug therapy, Malaria, Malaria vaccine, Malaria vaccines, Genetic research

---

Big pharma's commedia

Article Abstract:

The big pharmaceutical companies are facing an uncertain future, despite continuing financial success. The big pharma needs to pursue, merging basic and clinical research in a determined effort to fully elucidate the molecular mechanisms of disease to develop effective drugs with fewer side effects.

Forecasts, trends, outlooks, Financial management, Pharmaceutical preparations, Pharmaceutical industry, Finance, Company financing, Industry forecasts

Similar abstracts:

• Abstracts: Aspartate aminotransferase and tylosin biosynthesis in Streptomyces fradiae. Fluorinated vitamin B12 analogs are cofactors of corrinoid-dependent enzymes: a 19F-labeled nuclear magnetic resonance probe for identifying corrinoid-protein interactions
• Abstracts: Discovery of a new source of rifamycin antibiotics in marine sponge actinobacteria by phylogenetic prediction
• Abstracts: Validating the self-reported fertility status of rural Malawian women. They also serve: Chamorro male fertility in the pre-World War II period
• Abstracts: Harnessing viral devices as pharmaceuticals: Fighting HIV-1's fire with fire. Thinking big about global health

This website is not affiliated with document authors or copyright owners. This page is provided for informational purposes only. Unintentional errors are possible.