Selector genes and limb identity on arthropods and vertebrates
Article Abstract:
A study was conducted to determine the selector genes and limb identity of arthropods and vertebrates. Results revealed that differences in morphology of arthropod appendages that include the legs, antennae, tetrapod forelimb and hindlimb are controlled by homeotic (Hox) genes. In vertebrates, it was observed that the Hox genes demonstrate conserved domains along the anteroposterior axis that causes morphological differences among vertebrates and their associated skeletal processes.
Publication Name: Cell
Subject: Biological sciences
ISSN: 0092-8674
Year: 1999
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Axis development and early asymmetry in mammals
Article Abstract:
Researches conducted on the formation of the embryonic axes in mammals have created a special problem since the patterning of the embryo itself is a relatively late event in development. Thus, by the time the embryo begins to acquire a pattern, the conceptus is already a complex structure and implanted in the uterus. An analysis of the mouse development shows that the pattern in the fertilized egg could determine the axes of the conceptus as well as those of the embryo.
Publication Name: Cell
Subject: Biological sciences
ISSN: 0092-8674
Year: 1999
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Axis formation- beta-catenin catches a Wnt
Article Abstract:
The Heasman group implicates Wnt11 as a component of the canonical Wnt signaling pathway that specifies Xenopus laevis axis formation. This important work not only identifies a long-sought-after dorsalizing factor but also highlights the pivotal role of extracellular cofactors ion specifying the activation of either canonical or noncanonical Wnt pathways.
Publication Name: Cell
Subject: Biological sciences
ISSN: 0092-8674
Year: 2005
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