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A role for microRNAs in maintenance of mouse mammary epithelial progenitor cells

Article Abstract:

Analysis of mutations in key RNA interference components indicates a role of microRNAs (miRNAs) in the maintenance and differentiation of mammary epithelial progenitor cells. miRNA expression pattern forms both a characteristic signature of a given cell type and helps reinforce cell fate specification.

Author: Sachidanandam, Ravi, Muthuswamy, Senthil K., Ibarra, Ingrid, Erlich, Yaniv, Hannon, Gregory
Publisher: Cold Spring Harbor Laboratory Press
Publication Name: Genes & Development
Subject: Biological sciences
ISSN: 0890-9369
Year: 2007
Epithelial cells, Gene expression, Mutation (Biology), Mutation, RNA interference

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Jmjd1a and jmjd2c histone H3 Lys 9 demethylases regulate self-renewal in embryonic stem cells

Article Abstract:

A study observed the phenomenon of embryonic stem cells, which possessed the ability of self-renewal and pluripotency. The results showed that an embryonic stem cell transcription factor regulated a novel pathway that specified the epigenetic status of pluripotency-associated genes.

Author: Xi Chen, Huck-Hui Ng, Yuin-Han Loh, Weiwei Zhang, George, Joshy
Publisher: Cold Spring Harbor Laboratory Press
Publication Name: Genes & Development
Subject: Biological sciences
ISSN: 0890-9369
Year: 2007
Analysis, Genetic transcription, Transcription (Genetics), Precipitation (Chemistry), Antigen-antibody reactions, Embryonic stem cells

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Subjects list: Research, Genetic aspects
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