Stromal fibroblasts present in invasive human breast carcinomas promote tumor growth and angiogenesis through elevated SDF-1/CXCL12 secretion
Article Abstract:
The carcinoma -associated fibroblasts (CAFs) extracted from human breast carcinomas promotes the growth of admixed breast carcinoma cells significantly more than normal mammary fibroblasts derived from the same patients. The demonstration showed that the fibroblasts within invasive breast carcinomas contribute to tumor promotion in large part through the secretion of SDF-1.
Publication Name: Cell
Subject: Biological sciences
ISSN: 0092-8674
Year: 2005
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A lost generation
Article Abstract:
The funding policies of the National Institutes of Health (NIH) have made it very difficult for young researchers to procure research funds for basic biomedical research. The difficulties faced by the young researchers while obtaining their first R01 award from the NIH are discussed.
Publication Name: Cell
Subject: Biological sciences
ISSN: 0092-8674
Year: 2006
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Twist, a master regulator of morphogenesis, plays an essential role in tumor metastasis
Article Abstract:
The transcription factor Twist plays an important role in metastasis. The molecular actions of Twist and its involvement in human breast cancer pathogenesis are characterized.
Publication Name: Cell
Subject: Biological sciences
ISSN: 0092-8674
Year: 2004
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- Abstracts: Biochemical and genetic analysis of the yeast proteome with a movable ORF collection. tRNA (super His), maturation: an essential yeast protein catalyzes addition of a guanine nucleotide to the 5' end of tRNA (super His)
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