Structural features of the glutamate transporter family
Article Abstract:
Neuronal and glial glutamate transporters remove the excitatory neurotransmitter glutamate from the synaptic cleft. The proteins belong to a large family of secondary transporters that include serine, bacterial glutamate and C4-dicarboxylate transporters. Moreover, the homology between family members is the most significant in a stretch of about 150 residues in the C-terminal portion of the proteins.
Publication Name: Microbiology and Molecular Biology Reviews
Subject: Biological sciences
ISSN: 1092-2172
Year: 1999
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The 2-hydroxycarboxylate transporter family: Physiology, structure, and mechanism
Article Abstract:
The knowledge about the 2-hydroxycarboxylate transporter (2HCT) family, a family of secondary transporters is reviewed. Transporters of the 2HCT family are found exclusively in the bacterial kingdom, predominantly in the class Bacillales of the phylum Firmicutes and the beta and gamma subdivisions of the phylum Protebacteria, where they function in the specific niches.
Publication Name: Microbiology and Molecular Biology Reviews
Subject: Biological sciences
ISSN: 1092-2172
Year: 2005
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Membrane topology and insertion of membrane proteins: search for topogenic signals
Article Abstract:
Biochemical methods for determining membrane protein topology and insertion are described. Understanding the mechanisms of insertion will allow scientists to predict the three-dimensional structure of the protein from its amino acid sequence.
Publication Name: Microbiology and Molecular Biology Reviews
Subject: Biological sciences
ISSN: 1092-2172
Year: 2000
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