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Subventricular zone astrocytes are neural stem cells in the adult mammalian brain

Article Abstract:

A study was conducted to show that subventricular zone astrocytes remain labeled with proliferation markers after long survivals in adult mice. An antimitotic treatment was utilized to eliminate immature precursors and neuroblasts. Results indicated that the astrocytes infected with a retrovirus promote unique neurons in the olfactory bulbs and give rise to cells that grow into multipotent neurospheres in vitro.

Author: Alvarez-Buylla, Arturo, Doetsch, Fiona, Caille, Isabelle, Lim, Daniel A., Garcia-Verdugo, Jose Manuel
Publisher: Elsevier B.V.
Publication Name: Cell
Subject: Biological sciences
ISSN: 0092-8674
Year: 1999
Analysis, Physiological aspects, Mice, Mice (Rodents), Brain, Astrocytes

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Decapentaplegic is essential for the maintenance and division of germline stem cells in the Drosophila ovary

Article Abstract:

A study was conducted to examine the role of the BMP2/4 homolog decapentaplegic in maintaining female germline stem cells and promoting their division. Results indicated that the overexpression of dpp results into overian stem cell tumors. Findings also showed that the downstream components of the dpp signaling pathway are needed cell-autonomously in the germlin stem cells for their division and maintenance.

Author: Spradling, Allan C., Xie, Ting
Publisher: Elsevier B.V.
Publication Name: Cell
Subject: Biological sciences
ISSN: 0092-8674
Year: 1998
Genetic aspects, Ovaries, Drosophila

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Subjects list: Research, Stem cells
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