The Drosophila light-activated conductance is composed of the two channels TRP and TRPL
Article Abstract:
The Drosophila light-activated conductance is constituted by the transient receptor potential (TRP) and TRP-like (TRP-L) ion-channels that have partially overlapping functions. TRPL has 40% amino acid identity with TRP. TRP and TRPL are capable of independent response to light-activation, and are coexpressed along with phospholipase C and rhodopsin in the membranes of the transducing organelles. The light-activated channels are not gated by store-operated calcium release mechanisms or cyclic guanosine monophosphate.
Publication Name: Cell
Subject: Biological sciences
ISSN: 0092-8674
Year: 1996
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GPCR signaling is required for blood-brain barrier formation in Drosophila
Article Abstract:
The G protein-coupled receptor (GPCR) Moody, the G protein subunits Galphai Loco are required in the surface glia to achieve effective insulation. A study demonstrates the importance of morphogenetic regulation in the blood-brain barrier development and places GPCR signaling at its core.
Publication Name: Cell
Subject: Biological sciences
ISSN: 0092-8674
Year: 2005
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