Proteins complexed to the P1 adhesion of Mycoplasma pneumoniae

Article Abstract:

Researchers describe the proteins that complex to the P1 adhesion of Mycoplasma pneumoniae. They include the cytoskeleton-associated 65 kDa protein, the cytoskeleton-forming proteins HMW1 and HMW3, the chaperone DnaK, and the E1alpha subunit of pyruvate dehydrogenase.

Cell adhesion

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The Mycoplasma hominis P120 membrane protein contains a 216 amino acid hypervariable domain that is recognized by the human humoral immune response

Article Abstract:

Mycoplasma hominis 7488 encodes a 120 kDa polypeptide which has a hypervariable part that is recognized by the human humoral immune response. This domain may be essential in evading the host's immune response and helps in the survival of the pathogen. The heterogeneity of the hypervariable domain was confirmed by the gene fragments that are amplified from M. hominis isolates via PCR.

Analysis, Immune response

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Mycoplasma synoviae surface protein MSPB as a recombinant antigen in an indirect ELISA

Article Abstract:

Research was conducted to determine the most antigenic region of MSPB and to evaluate the potential of a serological test based on the antigen, in comparison to the RSA. A comparison of the RU values of the sera taken from chickens collected at various time points after inoculation with Mycoplasma synoviae revealed that MSPB antibodies could be detected by day 7 post-inoculation. Results indicate that the MSPB-ELISA could be sensitive as the RSA in its ability to detect M. synoviae antibodies in chicken sera early in infection.

Enzyme-linked immunosorbent assay, Pathogenic microorganisms, Parasite antigens

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