The highly ordered double-stranded RNA genome of bluetongue virus revealed by crystallography
Article Abstract:
A study was conducted to examine the structure of the bluetongue virus core serotype 10. Using X-Ray crystallography, it was revealed that the blue tongue virus' core contains a highly-ordered double-stranded RNA genome. Measurements provided by power diffraction rings showed that the double-stranded RNA maintains a 30 A separation between strands. The study also found that genome segments' local ordering occur during genetic transcription.
Publication Name: Cell
Subject: Biological sciences
ISSN: 0092-8674
Year: 1999
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The crystal structure of plasma gelsolin: implications for actin severing, capping and nucleation
Article Abstract:
Crystallography was employed to determine the crystal structure of plasma gelsolin. Six structurally-related domains were observed. Ca2+ binding was proposed for releasing the connections that bind gelsolin's N- and C-terminal halves and enable each half to independently bind actin. Domain shifts are also proposed for modeling the function of gelsolin to to cap, sever and nucleate F-actin filaments.
Publication Name: Cell
Subject: Biological sciences
ISSN: 0092-8674
Year: 1997
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Atomic snapshots of an RNA packaging motor reveal conformational changes linking ATP hydrolysis to RNA translocation
Article Abstract:
The crystallographic structures of ATPase P4 are examined along the catalytic pathway, including apo, substrate analog bound, and product bound. These structures reveal large movements of the putative RNA binding loop.
Publication Name: Cell
Subject: Biological sciences
ISSN: 0092-8674
Year: 2004
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