Tri1 encodes the cytochrome P450 monooxygenase for C-8 hydroxylation during trichothecene biosynthesis in Fusarium sporotrichioides and resides upstream of another new Tri gene

Article Abstract:

Research shows that Tri1 gene, encoding P450 monooxygenase, is essential for the biosynthesis of trichothecene as demonstrated by Tri1 gene encoding a C-8 hydroxylase, involved in the production of C-8-oxygenated trichothecenes. Tri1 is localized to a distal part of the trichothecene gene cluster or in another trichothecene gene cluster in Fusarium sporotrichioides.

Fusarium

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Identification of new genes positively regulated by Tri10 and a regulatory network for trichothecene mycotoxin production

Article Abstract:

Research has been conducted on regulatory genes from trichothecene mycotoxin-producing Fusarium species which is required for trichothecene biosynthesis. Results demonstrate that these genes regulate overlapping set of genes which include multiple genes for primary and secondary metabolism.

Analysis, Environmental aspects, Microbiology, Metabolism, Genetic regulation, Microbial genetics, Microbial ecology, Overlapping genes

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A novel regulatory gene, Tri10, controls trichothecene toxin production and gene expression

Article Abstract:

Researchers describe a regulatory gene, Tri10, in Fusarium sporotrichioides that regulates four trichothecene genes and the gene for farnesyl pyrophosphate synthetase. It also makes the fungus resistant to T-2 toxin.

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