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Genomic biology

Article Abstract:

Genomics is changing biology and the understanding of it, and in the future, to figure out what meaning data have, genomic researchers will have to look back at the development of biology as a science. New ways to handle and isolate the right sets of information and new heuristics for reasoning from information and planning new experiments will be found. As genomic inventories approach closure, the mass of data will create the need to find computational frameworks to put together biological data about cell components and to try to predict system behavior. Design-based biological engineering of cells/organisms may give rise to cells and organisms for new functions.

Author: Brent, Roger
Publisher: Elsevier B.V.
Publication Name: Cell
Subject: Biological sciences
ISSN: 0092-8674
Year: 2000
Forecasts and trends, History, Mice, Mice (Rodents), Developmental biology, Fluorescence microscopy, Genetic regulation, Genomes, Biology, Mutation (Biology), Mutation, Caenorhabditis elegans, Biological research, Embryology, Animal embryology, Genetic polymorphisms

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The impact of comparative genomics on our understanding of evolution

Article Abstract:

Comparative genomics and its impact on the understanding of evolution are discussed. In 2100 ancient families of orthologs identified by comparing 21 archaeal, bacterial, and eukaryotic genomes, only 80 are found in each organism. Yet genome comparisons show the great unity of all living things. Most of the universal families have core components of the translation and transcription mechanisms. Researchers now know that there is no true understanding of the connection between genome and phenotype in an organism. This is in some sense the central theme of biology. It can be solved only by using an experimental program based on comparative-genomic results.

Author: Koonin, Eugene V., Aravind, L., Kondrashov, Alexey S.
Publisher: Elsevier B.V.
Publication Name: Cell
Subject: Biological sciences
ISSN: 0092-8674
Year: 2000
Bacterial genetics, Phenotype, Cladistic analysis, Phenotypes, Cytogenetics

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Yeast Cbk1 and Mob2 activate daughter-specific genetic programs to induce asymmetric cell fates

Article Abstract:

Research has been conducted on the gene expression in daughter cells. Results indicate that some daughter-specific gene products separate cells via degrading the septum from the daughter side of the mother-daughter pair.

Author: Brent, Roger, Colman-Lerner, Alejandro, Chin, Tina E.
Publisher: Elsevier B.V.
Publication Name: Cell
Subject: Biological sciences
ISSN: 0092-8674
Year: 2001
Analysis, Physiological aspects, Gene expression, Cell research, Cytological research

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Subjects list: Research, United States, Usage, Genetic aspects, Evolution (Biology), Cytochemistry, Chromosome mapping, Evolution, Yeast, Yeast (Food product)
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