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A cool way to make proteins

Article Abstract:

The 'pCold' vector system when utilized at the right temperature reduces the expression of endogenous bacterial proteins and it might also reduce the various problems put together. Once this cold shock is performed the bacterial cells change to machines that produce protein and is dedicated solely to creating recombinant protein.

Author: Schein, Catherine H.
Publisher: Nature Publishing Co.
Publication Name: Nature Biotechnology
Subject: Business
ISSN: 1087-0156
Year: 2004
Manufacturing processes, Risk factors, Production processes, Proteins, Varieties, Recombinant proteins

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New antibiotics from bacterial natural products

Article Abstract:

The naturally occurring antibiotics from both new and old sources are rediscovered with unique scaffolds and novel mechanisms of action. The newly discovered antibiotics would provide valuable clues about the bacterial targets against which natural product and synthetic chemical libraries should be screened.

Author: Clardy, Jon, Walsh, Christopher T., Fischbach, Michael A.
Publisher: Nature Publishing Co.
Publication Name: Nature Biotechnology
Subject: Business
ISSN: 1087-0156
Year: 2006

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Beyond interferon

Article Abstract:

Interferon (IFN)-alpha has ruled as the biotech antiviral market since its identification fifty years ago. However, the various antibody treatments and nucleic acid therapies targeting cellular proteins and viral components by the new generation biotech firm may change the scenario.

Author: Salfeld, Jochen G
Publisher: Nature Publishing Co.
Publication Name: Nature Biotechnology
Subject: Business
ISSN: 1087-0156
Year: 2007
Usage, Interferon alpha

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Subjects list: Research, United States, Bacterial proteins, Antibiotics
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