Induction of human cytotoxic T lymphocytes by artificial antigen-presenting cells

Article Abstract:

A promising therapeutic approach for a number of diseases can be found in the adoptive transfer of antigen-specific cytotoxic T lymphocytes (CTLs). Stable artificial antigen-presenting cells (AAPCs) that can be used to stimulate T cells in any patient of a given human leukocyte (HLA) type are estabblished, thuis overcoming the difficulty in generating specific CTLs.

Research and Development in the Physical, Engineering, and Life Sciences, Research and Testing Services, Biological Product (except Diagnostic) Manufacturing, Surgical and Medical Instrument Manufacturing, Surgical and medical instruments, Biological products exc. diagnostic, Cancer & Cell R&D, Source Leukocytes, Antigen Detection Tests, Cancer research, Medical testing products, Immunologic tests, Blood products

---

The ABCs of artificial antigen presentation

Article Abstract:

Artificial antigen presentation helps in increasing the speed of establishment of therapeutic cellular immunity and the artificial antigen-presenting cells (AAPCs) stimulate the expansion of the optimal therapeutic features of T cells before therapeutic infusion. Artificial antigen-presenting systems consist of cell-based and acellular technologies, which focus on potency, antigen specificity and biosafety as measures for possible clinical use.

Analysis, T cells, Cell research, Cytological research, Antigen-antibody reactions

---

A genetic strategy to treat sickle cell anemia by coregulating globin transgene expression and RNA interference

Article Abstract:

A genetic strategy to treat sickle cell anemia by coregulating globin transgene expression and RNA interference is presented. The strategy demonstrates the feasibility and therapeutic potential of coregulating transgene expression and RNA interference in hematopoietic stem cells.

Gene expression, Hematopoietic stem cells, RNA interference

Similar abstracts:

• Abstracts: Genomic integration and gene expression by a modified adenoviral vector. Genomic integration and gene expression by modified adenoviral vector
• Abstracts: Total cost of ownership: the cost of being a networked professional. VPNs: secure communications for a networked professional
• Abstracts: On-site photofinishing services versus Internet opportunities. Online pro services vs traditional photo labs
• Abstracts: Tumor angiogenesis-new drugs on the block: angeogenisis inhibitors could represent adjunct to traditional cancer treatments, but the most effective routes for therapeutic intervention remain unclear
• Abstracts: Who's your neighbor? New computational approaches for functional genomics? Large-scale functional analysis using peptide or protein arrays

This website is not affiliated with document authors or copyright owners. This page is provided for informational purposes only. Unintentional errors are possible.