An explosive-degraded cytochrome P450 activity and its targeted application for the phytoremediation of RDX
Article Abstract:
The P450 domain of xplA is fused to a flavodoxin redox partner and the degradation of hexahydro-1,3,5-trinitro-1,2,3-triazine (RDX) in the absence of oxygen is demonstrated to investigate the potential of plants to remove RDX from contaminated soil and water. The results revealed that expression of xplA in landscape plants may provide a suitable remediation strategy for sites contaminated by RDX class explosives.
Publication Name: Nature Biotechnology
Subject: Business
ISSN: 1087-0156
Year: 2006
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Para-position derivatives of fungal anthelmintic cyclodepsipeptides engineered with Streptomyces venezuelae antibiotic biosynthetic genes
Article Abstract:
The PF1022A derivatives are a result of the changes in the benzene ring at the para-position with nitro or amino groups that pose as the raw material for the synthesis of compounds for better anthelmintic movements. From Streptomyces venezuelae antibiotic three genes are replicated and required for the biosynthesis of p-aminophenylpyruvate from chorismate in the chloramphenicol biosynthetic line.
Publication Name: Nature Biotechnology
Subject: Business
ISSN: 1087-0156
Year: 2004
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Identification of a cyclohexylcarbonyl CoA biosynthetic gene cluster and application in the production of doramectin
Article Abstract:
A cyclohexanecarboxylic acid (CDC)-derived moiety is contained in the side chain of the antifungal antiobiotic ansatrienin A from Strepomyces collinus.
Publication Name: Nature Biotechnology
Subject: Business
ISSN: 1087-0156
Year: 2000
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