Analysis of vertebrate SCL loci identifies conserved enhancers

Article Abstract:

Research focused on the analysis of vertebrate SCL loci identifies conserved enhancers. The combination of long-range comparative sequence analysis with a high-throughput transgenic bioassay offers a good strategy for identifying and characterizing developmentally significant enhancers.

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Synthesis of positional-scanning libraries of fluorogenic peptide substrates to define the extended substrate specificity of plasmin and thrombin

Article Abstract:

Research focusing on the development of a strategy for the synthesis of positional-scanning synthetic combinatorial libraries (PS-SCL) of fluorogenic peptide substrates to define the extended substrate specificity of plasmin and thrombin.

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Rationally designed anti-HER2/neu peptide mimetic disables P185HER2/neu tyrosine kinases in vitro and in vivo

Article Abstract:

Research focusing on the development of a small exocyclic anti-HER2/neu peptide mimic (AHNP). Researchers used a structure-based approach.

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Subjects list: United States, Brief Article
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