Protein analysis on a proteomic scale

Article Abstract:

Protein analysis on a proteomic scale consists of defining the identities, quantities, structures and functions of complete complements of proteins and how to characterize how these properties vary in different cellular contexts. Various technologies and strategies for protein analysis with their advantages and disadvantages are stated.

Author: Fields, Stanley, Snyder, Michael, Phizicky, Eric, Bastiaens, Philippe I.H., Zhu, Heng
Analysis, Proteins, Structure

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Analyzing antibody specificity with whole proteome microarrays

Article Abstract:

Proteome array technology has potential to improve antibody design and selection for applications medicine and research. Findings reveal that antibody screening experiments can be useful for revealing protein-protein interactions and provides new insights into biology.

Author: Snyder, Michael, Michaud, Gregory A., Salcius, Michael, Zhou, Fang, Bonin, Jaclyn, Guo, Hong, Predki, Paul F., Schweitzer, Barry I.

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Analyzing antibody specificity with whole proteome microarrays

Article Abstract:

The antibody specificity is analyzed with an array containing every protein for the relevant organism. The analysis shows that proteome array technology can be used to improve antibody design and selection for applications in both medicine and research.

Author: Hong Guo, Snyder, Michael, Michaud, Gregory A., Salcius, Michael, Schweitzer, Barry I., Bangham, Rhonda, Fang Zhou, Predki, Paul
Tumor antigens, Tumour antigens

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Subjects list: Research, United States, Biotechnology industry, Biotechnology industries, Technology application, Proteomics, Viral antibodies, Antibodies
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