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The pharmacological basis of anti-IgE therapy

Article Abstract:

Unique, humanized anti-IgE monoclonal antibodies are found to be useful in the treatment of asthma and allergic rhinitis according to the results of multiple phase II and III human clinical studies.

Author: Chang, Tse Wen
Publisher: Nature Publishing Co.
Publication Name: Nature Biotechnology
Subject: Business
ISSN: 1087-0156
Year: 2000
Taiwan, Antiasthmatic Preparations, Antiasthmatic agents

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CD18 trials disappoint again

Article Abstract:

Genentech's anti-CD18 monoclonal antibodies, designed for use in treating heart attacks, perform poorly in a phase II trial, failing to improve blood flow within the 90 minute target range.

Author: Dove, Alan
Publisher: Nature Publishing Co.
Publication Name: Nature Biotechnology
Subject: Business
ISSN: 1087-0156
Year: 2000
Cardiovascular Preparations, Genentech Inc., Cardiovascular agents, GNE

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Growing pains for biopharmaceuticals. Biopharmaceuticals have provided a swift means of swelling pharmaceutical company pipelines, but they may not be such a fast "fix" for the industry in the future

Article Abstract:

This study examines the economic contribution of biotechnology (recombinant proteins, and monoclonal antibodies) and its impact upon drug development, and the pharmaceutical industry as a whole for the years 1982 through 2000.

Author: Ashton, Gabby
Publisher: Nature Publishing Co.
Publication Name: Nature Biotechnology
Subject: Business
ISSN: 1087-0156
Year: 2001
Research and Development in the Physical, Engineering, and Life Sciences, Market information - general, Genetic Engineering, Pharmaceutical Preparations, Drugs

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Subjects list: Therapeutics, Monoclonal antibodies, United States
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