Homogenous detection of unamplified genomic DNA sequences based on colorimetric scatter of gold nanoparticle probes
Article Abstract:
A spot-and-read colorimetric detection technique is developed to locate nucleic acid series depending on the distance-dependant optical features of gold nanoparticles. DNA-modified gold probes that undergo a color change, identify the aim of the nucleic acid targets that are easily visible when the solutions are observed on an illuminated glass waveguide.
Publication Name: Nature Biotechnology
Subject: Business
ISSN: 1087-0156
Year: 2004
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Profile of a bacterial tumor killer
Article Abstract:
Clostridium novyi-NT is engineered to be non-toxic by deleting major systemic toxin gene and is shown to eradicate tumors in mice. Engineered bacteria have great promise as cancer therapeutics and engineered Clostridium novyi would likely facilitate the development of bacterial cancer therapies.
Publication Name: Nature Biotechnology
Subject: Business
ISSN: 1087-0156
Year: 2006
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The complete genome sequence of the meat-borne lactic acid bacterium lactobacillus sakei 23K
Article Abstract:
Lactobacillus sakei is a psychrotrophic lactic acid bacterium found naturally on fresh meat and fish. Genome sequencing revealed a specialized metabolic repertoire, including purine nucleoside scavenging that may contribute to an ability to successfully compete on raw meat products.
Publication Name: Nature Biotechnology
Subject: Business
ISSN: 1087-0156
Year: 2005
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