Feeder-free growth of undifferentiated human embryonic stem cells

Article Abstract:

Undifferentiated human embryonic stem cells are successfully grown in culture without the use of mouse embryonic fibroblast feeders.

Author: Chunhui Xu, Inokuma, Margaret S., Denham, Jerrod, Golds, Kathaleen, Kundu, Pratima, Gold, Joseph D., Carpenter, Melissa K.
Publisher: Nature Publishing Co.
Publication Name: Nature Biotechnology
Subject: Business
ISSN: 1087-0156
Year: 2001
Research and Development in the Physical, Engineering, and Life Sciences, Genetic Engineering, Cellular Biology, Statistical Data Included, Illustration, Cytology

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Characterization and culture of human embryonic stem cells

Article Abstract:

The assessment of human embryonic stem cells (hES) cells in the context of the ultimate use of the cells is discussed. It is suggested that examination of the epigenetic status of hES cells should also be included in the assessment of hES cell characteristics.

Author: Carpenter, Melissa K., Hoffman, Lisa M.
Publisher: Nature Publishing Co.
Publication Name: Nature Biotechnology
Subject: Business
ISSN: 1087-0156
Year: 2005
Analysis, Cell research, Cytological research

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Production of pancreatic hormone-expressing endocrine cells from human embryonic stem cells

Article Abstract:

A differentiation process is developed that converts human embryonic stem (hES) cells to endocrine cells capable of synthesizing the pancreatic hormones insulin, glucagon, somatostatin, pancreatic polypeptide and ghrelin. Production of these hES cell-derived endocrine cells represents a critical step in the development of a renewable source of cells for diabetes cell therapy.

Author: Bang, Anne G., Carpenter, Melissa K., Kroon, Evert, D'Amour, Kevin A., Agulnick, Alan D., Eliazer, Susan, Kelly, Olivia G., Baetge, Emmanuel E., Smart, Nora G., Moorman, Mark A.
Publisher: Nature Publishing Co.
Publication Name: Nature Biotechnology
Subject: Business
ISSN: 1087-0156
Year: 2006
Somatostatin, Pancreatic hormone, Pancreatic hormones

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Subjects list: United States, Research, Embryonic stem cells
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